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In Vitro ADME Assays Predict PK Before Animal Studies

Solubility, permeability, and metabolic stability assays filter compounds for PK viability before expensive animal studies, using IVIVC to validate the predictions.

concept
pharmacokineticsdrug-discovery

Sources

Coursera: *Pharmacokinetics* (Introduction to Drug Hunting > Introduction to Drug Hunting, part 2), 2:18
Coursera: *In Vivo Pharmacokinetics* (Lead Selection & Optimization > Lead Selection & Optimization, part 3), 0:03