Therapeutic Index Measures Safety as Exposure Ratio
Therapeutic index (TI) compares the dose that causes harm to the dose that produces benefit; it's the quantitative expression of a drug's risk-benefit margin.
concept
drug-discoverymedicine
Sources
Coursera: *Therapeutic Index & Quantifying Safety* (Preclinical Safety > Preclinical Safety, part 2), 0:02
Coursera: *Therapeutic Index & Quantifying Safety* (Preclinical Safety > Preclinical Safety, part 2), 3:41